Rathmacher et al. At this time, a blood sample was obtained. failed to improve bench press strength compared with the placebo group [21], and we reasoned that a higher dosage may be necessary to demonstrate an effect of oral ATP on knee extension fatigue and strength. Both the placebo capsules containing rice flour and the ATP capsules containing 200 mg of Laboratory Consumables Peak ATP?were obtained from a commercial manufacturer (TSI (USA), Inc.
The current study was designed to test the hypothesis that supplemental ATP would improve performance of repeated high intensity exercise as measured by muscle torque, power, work and fatigue. Weight and height were measured and BMI was calculated.Rathmacher et al. Each participant participated in two experimental trials, one for each treatment, separated by at least one week for supplement wash out and recovery.
A washout period of at least 1 week separatedFigure 1 Timeline of experimental procedures. For each of the trials, participants refrained from vigorous exercise for three days before reporting to the laboratory in the morning after an overnight fast (Figure 1).Ss apparatus; however, no effect was observed at the lower dosage of 150 mg ATP per day. The protocol followed during each supplementation and testing period is shown in Figure 1. The ATP supplement was delivered as the disodium salt. All procedures involving human participants were approved by the Iowa State University Institutional Review Board,
and written informed consent was obtained from all participants prior to participation. During each trial participants were assigned to either: (a) 15 days oral ingestion of placebo; or (b) 15 days oral ingestion of 400 mg ATP/d with the dosage divided into two equal dosages, one in the morning and the other in the evening. Participants not able to meet the inclusion criteria were excluded from the study. Exercise consisting of light stretching and/or mild aerobic exercise lasting less than 45 minutes was allowed during this pre-study period.
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